IBC – Full Proposal Updated on: August 9, 2018 Please complete this form for the Institutional Biosafety Committee (IBC) to review prior to conducting your study. Please electronically submit this form with a copy of any other relevant forms, experimental protocols, or other materials to IBC chair’s email. Name(s) of Investigator(s): First Last Submitting Investigator’s email address: Submitting Investigator’s Austin College mailbox (Ste.#):Phone number:Project Title:Estimated Start Date: Date Format: MM slash DD slash YYYY Proposals may be approved for a maximum of three years.Estimated Completion Date: Date Format: MM slash DD slash YYYY This proposal is:New subject to current NIH guidelines section.Renewal of previously approved proposal.Modification of previously approved proposal.Title of New Subject:Previous approval date:The Project has been changed as follows: Protocol Modified: study methods Protocol Modified: study instruments Change in type or number of biological materials used Change in type or number of infectious agents used Change in investigators Category of Project:Faculty or Staff Research ProjectStudent Research ProjectClass Project (Faculty only)Department:Outside funding agency (if applicable):Course number and name (if applicable):Faculty or Staff Sponsor’s name (required):Sponsor’s email address (required):Sponsor’s AC mailbox (Ste. #) (required):Sponsor’s campus phone (required):Course number and name:Certification SignaturesIn submitting this proposal, I certify that I (and my co-investigators) have read and understand Austin College policies and procedures governing use of biohazardous materials, and I/we agree to abide by the policies and procedures. I certify that the attached information accurately describes the proposed use of biohazardous materials.Submitting Investigator’s NameIf a student project: I have read the attached information. In my opinion, it accurately describes the project, and the research will comply with College policies and procedures governing use of biohazardous materials. I accept responsibility for supervising the student’s conduct of the research. Faculty or Staff Sponsor’s NameFaculty/staff sponsor should send an email accepting responsibility to the IBC chair in lieu of signature.Type of Biohazard:Recombinant DNA or Artificial Gene Transfer such as (but not limited to) plasmid construction and interspecies gene transferBiological Toxins such as (but not limited to) botulism and other bacterial toxinsInfectious Agent such as (but not limited to) Shigella and StaphylococcusIndicate Appropriate Level of Activity:Risk Group 1 (low individual and community risk): a. Agents are not associated with disease in healthy adult humans; b. See BSL-1 LINK for specific classifications.Risk Group 2 (moderate individual risk, limited community risk): a. agents are associated with human disease which is rarely serious and for which preventive or therapeutic interventions are often available; b. See BSL-2 LINK for specific classifications.Summary Description of Biological Materials Used in ProjectDescribe the recombinant DNA material used in the proposed work (cloned gene(s) and vectors used – give both name and type of each vector).Which of the genes described above will be expressed?What organism(s) or cell lines are used in the proposed work?Describe any infectious or pathogenic agents used in the proposed work.List any materials of human or mammalian origin (blood, etc.). Indicate whether each material is certified pathogen free. Please provide copies of documentation that certifies cell lines are pathogen free.Methods Used to Contain Biohazards: Describe methods for containment and disposal of biohazardous materials.Investigators: List the names of all individuals participating in the proposed procedures, indicating their specific responsibilities. For each individual listed provide the dates and types of safety and biohazard training he/she has completed. All investigators will need to undergo College approved training before working with biohazardous material. New investigators can be included in your annual report at the end of each academic year.Additional Review: Have you submitted this research proposal for review by theIRBIACUCGuidelines for Project DescriptionsYour project description helps the Institutional Biosafety Committee to understand your project. A clear description facilitates the review. Please consider these topics as you compose your description:Describe the project. It helps to give some information about the purpose and rationale for the project. Describe the procedure clearly enough so that the IBC can understand exactly how the biohazards will be used and contained.Researchers who utilize biohazards face a challenge not faced by other researchers, namely, to address the issue of containment and disposal. Please include information about containment and disposal.Rationale for use of biohazards: include a justification for why biohazardous materials must be used for this study. Include possible alternatives to using biohazardous materials and the reasons for rejection of these alternatives.